Active
Bubble Knock Out 1.8% Salicylic Acid Acne Spot Treatment with Wintergreen & Willow Bark Extract
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Based on analysis of over 10,000 products. Typical price range defined as the 25th to 75th percentile.
A active priced at $7.5-10.0 is considered budget-friendly. Generally, actives cost between $24 and $68, and have an average price of $52.
Overview of the highest quality evidence for the active ingredients in this product
Shalita, A. R. Treatment of mild and moderate acne vulgaris with salicylic acid in an alcohol-detergent vehicle. Cutis. 1981;28(5):556-558, 561.
Lu J, Cong T, Wen X, Li X, Du D, He G, Jiang X. Salicylic acid treats acne vulgaris by suppressing AMPK/SREBP1 pathway in sebocytes. Exp Dermatol. 2019 Jul;28(7):786-794. doi: 10.1111/exd.13934. Epub 2019 May 15. PMID: 30972839.
Sarkar R, Ghunawat S, Garg VK. Comparative Study of 35% Glycolic Acid, 20% Salicylic-10% Mandelic Acid, and Phytic Acid Combination Peels in the Treatment of Active Acne and Postacne Pigmentation. J Cutan Aesthet Surg. 2019 Jul-Sep;12(3):158-163. doi: 10.4103/JCAS.JCAS_135_18. PMID: 31619887; PMCID: PMC6785964.
Liu H, Yu H, Xia J, Liu L, Liu G, Sang H, Peinemann F. Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. J Evid Based Med. 2020 Nov;13(4):275-283. doi: 10.1111/jebm.12411. Epub 2020 Oct 9. PMID: 33034949.
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